CANCER RESEARCH INSTITUTE INC

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Financial Vulnerability Assessment (Tuckman-Chang)

4 risk indicators measuring financial stability and operational resilience

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Financial Trends

Organization Details

Formation Year

1953

Legal Domicile

Principal Officer

ALICIA ZHOU PHD

Phone

2126887515

Tax Period

2023-07-01 to 2024-06-30

CANCER RESEARCH INSTITUTE INC, founded in 1953, is a mid-sized nonprofit in the Medical Research sector that reported $24.0M in total revenue in fiscal year 2023. Revenue fell 26% from the prior year — a significant decline worth monitoring. Expenses of $32.8M exceeded revenue, resulting in a 37% operating deficit.

Mission

THE CANCER RESEARCH INSTITUTE'S MISSION IS TO SAVE MORE LIVES BY FUELING THE DISCOVERY AND DEVELOPMENT OF POWERFUL IMMUNOTHERAPIES FOR ALL TYPES OF CANCER. TO ACCOMPLISH THIS, CRI FUNDS LABORATORY, TRANSLATIONAL, AND CLINICAL RESEARCH. EFFORTS AIMED AT LEARNING HOW TO HARNESS THE POWER OF THE IMMUNE SYSTEM TO DIAGNOSE, TREAT, AND CURE CANCER. CRI ALSO COORDINATES SCIENTIFIC, MEDICAL, AND PATIENT EDUCATION CONFERENCES ON THE SUBJECTS OF IMMUNOLOGY AND IMMUNOTHERAPY, AND DISSEMINATES INFORMATION IN ENGLISH AND SPANISH ABOUT ADVANCES IN TUMOR IMMUNOLOGY TO THE MEDIA, PUBLIC, AND MEDICAL AND SCIENTIFIC COMMUNITIES.

Program Service Accomplishments

Program 1

Expenses: $6,250,000

STAR PROGRAM - SEE SCHEDULE OTHE LLOYD J. OLD STAR PROGRAM PROVIDES GRANTS OF $1.25 MILLION OVER 5 YEARS TO MID-CAREER SCIENTISTS. THIS LONG-TERM FUNDING IS NOT TIED TO A SPECIFIC RESEARCH PROJECT...

STAR PROGRAM - SEE SCHEDULE OTHE LLOYD J. OLD STAR PROGRAM PROVIDES GRANTS OF $1.25 MILLION OVER 5 YEARS TO MID-CAREER SCIENTISTS. THIS LONG-TERM FUNDING IS NOT TIED TO A SPECIFIC RESEARCH PROJECT, BUT RATHER AIMS TO PROVIDE A DEGREE OF FLEXIBILITY AND FREEDOM FOR INVESTIGATORS TO EXPLORE OUTSIDE-THE-BOX AND DISRUPTIVE AVENUES OF RESEARCH. CANDIDATES SELECTED FOR THIS AWARD ARE EXPECTED TO BE FUTURE "STARS" IN THE FIELD OF CANCER IMMUNOLOGY: SCIENTISTS TAKING RISKS.

Program 2

Expenses: $6,133,761

FELLOWSHIP PROGRAM - SEE SCHEDULE OTHE CRI POSTDOCTORAL FELLOWSHIP PROGRAM INCLUDES THREE TRACKS OF FELLOWSHIPS PROVIDING CAREER DEVELOPMENT, TRAINING, AND DIVERSITY BUILDING IN IMMUNOLOGY AND...

FELLOWSHIP PROGRAM - SEE SCHEDULE OTHE CRI POSTDOCTORAL FELLOWSHIP PROGRAM INCLUDES THREE TRACKS OF FELLOWSHIPS PROVIDING CAREER DEVELOPMENT, TRAINING, AND DIVERSITY BUILDING IN IMMUNOLOGY AND IMMUNO-INFOMATICS. THE CRI IRVINGTON POSTDOCTORAL FELLOWSHIP, CRI IRVINGTON POSTDOCTORAL FELLOWSHIP TO PROMOTE RACIAL DIVERSITY, AND THE CRI IMMUNO-INFORMATICS FELLOWSHIP EACH SUPPORT YOUNG IMMUNOLOGISTS AND CANCER IMMUNOLOGISTS AT TOP UNIVERSITIES AND RESEARCH CENTERS AROUND THE WORLD. FELLOWS RECEIVE UP TO $243,000 OVER THREE YEARS TO COVER THE COST OF STIPEND, INCLUDING AN INSTITUTIONAL ALLOWANCE TO HELP PAY FOR THE FELLOW'S RESEARCH SUPPLIES, TRAVEL TO SCIENTIFIC MEETINGS, HEALTH INSURANCE, AND/OR CHILDCARE. OF THE MORE THAN 1,620 CRI POSTDOCTORAL FELLOWS FUNDED TO DATE, MANY HAVE SINCE BECOME HEADS OF MAJOR MEDICAL RESEARCH INSTITUTES, ACADEMIC LEADERS IN PRESTIGIOUS UNIVERSITIES, AND ADMIRED MENTORS TO THE NEXT GENERATION OF IMMUNOLOGISTS AND TUMOR IMMUNOLOGISTS.

Program 3

Expenses: $2,979,640

CRI CLINICAL INNOVATOR - SEE SCHEDULE OTHE CRI CLINICAL INNOVATOR SUPPORTS NOVEL CLINICAL STUDIES THAT ADDRESS AREAS OF HIGH UNMET NEED IN CANCER AND SEEKS MECHANISTIC INSIGHTS INTO CLINICAL RESPONSE WITH A GOAL OF PREDICTIVE BIOMARKER DISCOVERY. TO MAXIMIZE THE IMPACT OF EACH CLINICAL TRIAL, CRI WILL ADVISE ON SELECTED STUDIES IN A COORDINATED EFFORT TO OPTIMIZE CLINICAL TRIAL DESIGN AND TRANSLATIONAL STUDIES. FUNDING OF UP TO $1M PER CLINICAL TRIAL IS AWARDED.

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Trantor Score

Financial Health Score (300–850) · Liquidity · Solvency · Sustainability · Efficiency

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Liquidity (40%) • Solvency (30%) • Sustainability (20%) • Efficiency (10%)

Financial Overview (2023)

Revenue Breakdown

Contributions & Grants $20,143,304

Program Service Revenue $0

Investment Income $3,783,274

Other Revenue $38,060

TOTAL REVENUE $23,964,638

Expense Breakdown

Grants Paid $22,471,018

Salaries & Benefits $5,354,714

Fundraising Expenses $3,445,611

Program Expenses $26,628,724

Other Expenses $4,995,164

TOTAL EXPENSES $32,820,896

Year-over-Year Comparison

	2023	2022	Change
Revenue	$23,964,638	$32,295,259	-0.3%
Expenses	$32,820,896	$38,552,663	-0.1%
Net Income	$-8,856,258	$-6,257,404	+0.4%

Key Indicators

✓ Grants to Organizations ✗ Grants to Individuals ✗ Lobbying ✗ Political Activity ✓ Foreign Activities ✗ Donor Advised Fund ✓ Schedule B Required

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Financial Health Indicators

Comprehensive financial analysis: Altman Z-Score, liquidity, solvency, sustainability, efficiency, and growth metrics

Financial Distress Indicator

Liquidity & Cash Position

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Altman Z-Score • Liquidity Ratios • Solvency Analysis • Growth Indicators • Efficiency Metrics

Governance

Voting Members

Independent Members

Employees

Volunteers

250

Governance Policies

✓ Conflict of Interest Policy

✓ Whistleblower Policy

✓ Document Retention Policy

Special Practices & Reported Activities

✗ Operated a School

✗ Operated a Hospital

✗ Provided First Class Travel

✗ Reported Conflict of Interest

✗ Reported Asset Diversion

✗ Excess Benefit Transaction

✗ Made Political Expenditures

✗ Engaged in Lobbying

✗ Operated Donor Advised Fund

✗ Maintained Art Collections

✗ Filed Form 720

Compensation of Officers, Directors & Key Employees

Total Officers

$1,049,619

Total Directors

Key Employees

$1,583,701

Highest Compensated

reported

Name	Title	Hours/Week	Role	Reportable Comp	Other Comp	Total
PAUL C SHIVERICK	CHAIRMEN	5.00	Officer Director	$0	$0	$0
ANDREW K TSAI	CHAIRMEN	5.00	Officer Director	$0	$0	$0
DONALD J GOGEL	VICE CHAIRMEN	3.00	Officer Director	$0	$0	$0
EDGAR R BERNER	VICE CHAIRMEN	3.00	Officer Director	$0	$0	$0
GEOFFREY O COLEY	TREASURER	3.00	Officer Director	$0	$0	$0
THOMAS G MENDELL	SECRETARY	1.00	Officer Director	$0	$0	$0
TONY ALVAREZ II	TRUSTEE	0.50	Director	$0	$0	$0
YACOV ARNOPOLIN	TRUSTEE	4.00	Director	$0	$0	$0
PETER L BLOOM	TRUSTEE	4.00	Director	$0	$0	$0
BRIAN J BRILLE	TRUSTEE	1.00	Director	$0	$0	$0
MICHAEL R CRAWFORD	TRUSTEE (THRU 4/2024)	1.00	Director	$0	$0	$0
W ROBERT DAHL	TRUSTEE	1.00	Director	$0	$0	$0
MAXWELL DAVID	TRUSTEE	0.25	Director	$0	$0	$0
GLENN J DESIMONE	TRUSTEE (THRU 7/2023)	1.00	Director	$0	$0	$0
SEAN P FAHEY	TRUSTEE	1.00	Director	$0	$0	$0
WILLIAM S GOLDBERG	TRUSTEE	0.25	Director	$0	$0	$0
OLIVER R GRACE JR	TRUSTEE	1.00	Director	$0	$0	$0
SANDRA COUDERT GRAHAM	TRUSTEE	0.50	Director	$0	$0	$0
MICHAEL M KELLEN	TRUSTEE	1.00	Director	$0	$0	$0
SARAH KIM	TRUSTEE	3.00	Director	$0	$0	$0
FERN LAZAR	TRUSTEE	3.00	Director	$0	$0	$0
ALEXANDER P LYNCH	TRUSTEE (THRU 7/2023)	1.00	Director	$0	$0	$0
SANDRA OZOLA	TRUSTEE	0.25	Director	$0	$0	$0
MICHAEL J PETRICK	TRUSTEE	0.50	Director	$0	$0	$0
LIEF D ROSENBLATT	TRUSTEE	0.25	Director	$0	$0	$0
ANAND SHAH MD	TRUSTEE	0.25	Director	$0	$0	$0
ADAM SHAPIRO	TRUSTEE	0.25	Director	$0	$0	$0
FRANK V SICA	TRUSTEE	1.00	Director	$0	$0	$0
JAMES A STERN	TRUSTEE	1.00	Director	$0	$0	$0
ROBERT S STOLAR	TRUSTEE	1.00	Director	$0	$0	$0
MICHAEL B TARGOFF	TRUSTEE	1.00	Director	$0	$0	$0
DIANE TUFT	TRUSTEE	1.00	Director	$0	$0	$0
LAUREN S VERONIS	TRUSTEE	3.00	Director	$0	$0	$0
RONALD G WEINER	TRUSTEE	1.00	Director	$0	$0	$0
JIM WEISS	TRUSTEE	4.00	Director	$0	$0	$0
PETER ZHOU	TRUSTEE	5.00	Director	$0	$0	$0
ALFRED R MASSIDAS TO 22025	CFO & DIRECTOR OF HUMAN RESOURCES	40.00	Officer	$347,437	$90,161	$437,598
JILL O'DONNELL TORMEY TO 824	CEO & DIRECTOR OF SCIENTIFIC AFFAIRS	40.00	Officer	$539,137	$72,884	$612,021
ALICIA ZHOU PHD START 92024	CEO	40.00	Officer	$0	$0	$0
KATHRYN BEELEY START 22025	CFO	40.00	Officer	$0	$0	$0
DEANNE T MARBACH	DIRECTOR OF MAJOR GIFTS	40.00	Key Emp	$155,690	$54,575	$210,265
JAY R CAMPBELL	MANAGING DIR OF CRI CLINICAL ACCELERATOR	40.00	Key Emp	$284,937	$83,161	$368,098
LYNNE A RAPINO	CHIEF PROGRAM OFFICER	40.00	Key Emp	$287,287	$84,627	$371,914
RUPINDER KAUR	CHIEF INFORMATION OFFICER	40.00	Key Emp	$247,910	$64,351	$312,261
SHARON S SLADE	CHIEF MARKETING OFFICER	40.00	Key Emp	$273,403	$47,760	$321,163
BRIAN M BREWER	CHIEF COMMUNICATIONS OFFICER	40.00	Highest	$148,135	$0	$148,135
MARLA S LAWSON	ASSOC DIR OF CORPORATE RELATIONS	40.00	Highest	$136,015	$52,016	$188,031
QING HUA ZHANG	CONTROLLER	40.00	Highest	$147,203	$53,996	$201,199
SAMIK K UPADHAYA	ASST DIRECTOR, SCIENTIFIC AFFAIRS	40.00	Highest	$145,770	$54,210	$199,980
SHASELL NEGRON	ASSOC DIR, COMMUNITY FUNDRAISING	40.00	Highest	$126,437	$32,999	$159,436

Note: Compensation data is self-reported by the organization on their Form 990. "Reportable Comp" includes salary, bonuses, and other reportable compensation from the organization and related organizations. "Other Comp" includes benefits, deferred compensation, and non-taxable benefits.

Historical Data

Year	Revenue	Expenses	Assets	Net Income
2025	No data	No data	No data	No data
2024	$23,964,638	$32,820,896	$133,734,670	$-8,856,258
2023	$32,295,259	$38,552,663	$138,008,864	$-6,257,404
2022	$33,675,150	$31,314,716	$130,438,312	$2,360,434
2021	$35,987,695	$37,138,977	$146,547,886	$-1,151,282
2020	$37,223,458	$38,496,564	$126,564,196	$-1,273,106
2019	$41,995,692	$34,748,390	$127,608,094	$7,247,302