CLINTON HEALTH ACCESS INITIATIVE INC

OUR PROGRAMS AIM TO SAVE LIVES AND REDUCE THE BURDEN OF DISEASE, WHILE HELPING GOVERNMENTS CREATE SUSTAINABLE HEALTH SYSTEMS. WE OPERATE IN OVER 35 COUNTRIES AND SUPPORT MORE THAN 20 DIFFERENT HEALTH PROGRAMS. THE VAST MAJORITY OF OUR STAFF ARE LOCATED IN THE COUNTRIES WHERE WE WORK, OVERSEEING IMPLEMENTATION AND MANAGING RELATIONSHIPS WITH PARTNER GOVERNMENTS. THE TEAMS ON THE GROUND ARE COMPLEMENTED BY A GLOBAL TEAM OF SCIENCE, BUSINESS, AND TECHNICAL EXPERTS SUPPORTING THE ENTIRE ORGANIZATION AND BY MANAGEMENT, FINANCE, AND HUMAN RESOURCE TEAMS. INFECTIOUS DISEASES: SEE SCHEDULE O FOR CONTINUATIONINFECTIOUS DISEASES: FOR YEARS, FOUR INFECTIOUS DISEASES DROVE MOST ILLNESS AND DEATH WORLDWIDE: HIV, HEPATITIS, TUBERCUOSIS (TB), AND MALARIA. IN 2020, A NEW ILLNESS, COVID-19, WAS ADDED TO THIS LIST.EARLY ON, THE PANDEMIC BROUGHT MANY HEALTH SYSTEMS TO THEIR KNEES, AND IT CONTINUES TO EXPOSE AND EXACERBATE INEQUITIES THAT ALREADY EXISTED BETWEEN COUNTRIES, PEOPLE, AND ACCESS TO BASIC HEALTH SERVICES. IN 2023, CHAI CONTINUED TO SUPPORT COUNTRIES' LONGTERM RESPONSE TO COVID-19 AND STRENGTHEN HEALTH SYSTEM RESLIENCE TO PREPARE FOR FUTURE PANDEMICS.A CORE COMPONENT OF THIS WORK HAS BEEN STRENGTHENING ACCESS TO MEDICAL OXYGEN IN HEALTHCARE FACILITIES AND HOSPITALS IN LOW- AND MIDDLE-INCOME COUNTRIES THROUGH UPDATING INFRASTRUCTURE (I.E. BUILDING PRESSURE SWING ADSORPTION (PSA) PLANTS; SUPPORTING BEDSIDE DELIVERY OF LIQUID OXYGEN), KEEP OXYGEN EQUIPMENT UP AND RUNNING FOR ITS FULL LIFESPAN AND PROVIDING HEALTH WORKERS WITH THE RIGHT TOOLS, PROCESSES, AND PRACTICES TO SAVE LIVES.AT THE SAME TIME WE CONTINUE TO WORK ON THE DISEASE AREAS THAT WE HAVE FOCUSED ON FOR DECADES, INCLUDING HIV AND ADVANCED HIV DISEASE.FOR EXAMPLE, OUR WORK TO INTRODUCE AFFORDABLE, MORE PALATABLE HIV TREATMENTS FOR CHILDREN. THERE HAVE BEEN VAST IMPROVEMENTS IN PEDIATRIC HIV TREATMENT IN RECENT YEARS, INCLUDING THE RAPID DEVELOPMENT AND INTRODUCTION OF GENERIC PEDIATRIC DOLUTEGRAVIR TABLETS, WHICH DISSOLVE IN WATER AND TASTE LIKE STRAWBERRIES, DRAMATICALLY INCREASING CHILDREN'S ADHERENCE TO THEIR TREATMENT REGIMEN. CHAI IS WORKING WITH PARTNERS TO DRIVE THE DEVELOPMENT AND INTRODUCTION OF MORE GENERIC VERSIONS OF BEST-IN-CLASS CHILDREN'S MEDICATIONS.

WOMEN & CHILDREN'S HEALTH: SEE SCHEDULE O FOR CONTINUATIONWOMEN & CHILDREN'S HEALTH: WOMEN AND CHILDREN SUFFER THE GREATEST BURDEN FROM DISEASE GLOBALLY. CHAI HAS SIGNIFICANTLY INCREASED ACCESS TO RECOMMENDED TREATMENTS FOR DIARRHEA AND PNEUMONIA, THE LARGEST KILLERS OF CHILDREN UNDER FIVE; MADE CRITICAL VACCINES THAT PROTECT AGAINST CHILDHOOD ILLNESSES MORE AFFORDABLE; IS COMBATTING CHRONIC MALNUTRITION; AND IS DRAMATIALLY AND SUSTAINABLY REDUCING MATERNAL AND NEWBORN DEATHS AND ENSURING WOMEN HAVE ACCESS TO THE TOOLS THEY NEED TO SAFELY PLAN THER FAMILIES TO IMPROVE HEALTH OUTCOMES AND ECONOMIC WELLBEING.FOR EXAMPLE, WHEN CHAI BEGAN OUR DIARRHEA PROGRAM IN 2012, ONLY ONE-THIRD OF CHILDREN THAT NEEDED LIFESAVING ORAL REHYDRATION SOLUTIONS (ORS) RECEIVED IT. ZINC USAGE RATES WERE EVEN WORSE. THROUGH CHAI'S MARKET SHAPING WORK, WE HELPED REDUCE THE AVERAGE COST OF ZINC/ORS TREATMENT BY 42 PERCENT. WORKING WITH PARTNERS IN INDIA, KENYA, NIGERIA, AND UGANDA, WE ALSO INCREASED THE PERCENTAGE OF CHILDREN WITH DIARRHEA RECEIVING ZINC/ORS FROM LESS THAN ONE PERCENT TO 24 PERCENT.ANOTHER STRONG EXAMPLE IS CHAI'S WORK TO SAVE THE LIVES OF WOMEN AND NEWBORNS. CHAI HAS DEVELOPED AN INTEGRATED MATERNAL, NEWBORN, AND REPRODUCTIVE HEALTH STRATEGY THAT HAS CONTRIBUTED TO SUSTAINED AND SIGNFICANT REDUCTIONS IN DEATH IN COUNTRIES WHERE WE WORK. THIS APPROACH WAS FIRST PILOTED IN ETHIOPIA, BEFORE BEING TESTED AT SCALE IN NIGERIA, WHERE WE SAW A NEARLY 40 PERCENT REDUCTION IN MATERNAL MORTALITY AND A 43 PERCENT REDUCTION IN NEWBORN DEATHS IN A 12- MONTH PERIOD IN TARGET STATES OF NORTHERN NIGERIA. THE PROGRAM HAS BEEN ROLLED OUT MORE RECENTLY IN ZAMBIA AND UGANDA WITH SIMILAR RESULTS.