THE BIOMEDICAL RESEARCH INSTITUTE OF SOUTHERN CALIFORNIA

EIN: 452210161 501(c)(3) Medical Research

OCEANSIDE, CA

Total Revenue
$208,249
Total Expenses
$188,995
Total Assets
$60,330
Net Assets
$4,854
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Financial Vulnerability Assessment (Tuckman-Chang)

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Financial Trends

Organization Details

Formation Year
2011
Legal Domicile
CA
Principal Officer
SALLY SARAWAR
Phone
8887235830
Tax Period
2023-01-01 to 2023-12-31

THE BIOMEDICAL RESEARCH INSTITUTE OF SOUTHERN CALIFORNIA, founded in 2011, is a small nonprofit in the Medical Research sector that reported $208K in total revenue in fiscal year 2023. Revenue surged 188% from the prior year, signaling strong growth momentum. Expenses of $189K left a modest 9% surplus.

Mission

THE MISSION OF THIS ORGANIZATION IS TO CONDUCT SCIENTIFIC RESEARCH AIMED AT CURING OR PREVENTING HUMAN DISEASE. WE WILL CONDUCT BASIC RESEARCH AIMED AT UNDERSTANDING THE FUNDAMENTAL MECHANISMS OF NORMAL BIOLOGICAL PROCESSES AND HOW THESE DIFFER IN DISEASE STATES. THIS WILL HELP US TO IDENTIFY NEW WAYS TO DIAGNOSE, PREVENT OR TREAT HUMAN DISEASE. WE WILL ALSO CONDUCT PRECLINICAL DISCOVERY RESEARCH INTO DEVELOPING AND TESTING NOVEL VACCINES AND THERAPEUTIC AGENTS FOR HUMAN DISEASE.

Program Service Accomplishments

Program 1

VIRAL IMMUNOLOGYTHE OBJECTIVE OF THIS PROGRAM IS TO CONDUCT RESEARCH INTO THE MECHANISMS BY WHICH THE IMMUNE SYSTEM PROTECTS AGAINST VIRAL INFECTIONS. THIS RESEARCH WILL HELP US TO DEVELOP BETTER...

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VIRAL IMMUNOLOGYTHE OBJECTIVE OF THIS PROGRAM IS TO CONDUCT RESEARCH INTO THE MECHANISMS BY WHICH THE IMMUNE SYSTEM PROTECTS AGAINST VIRAL INFECTIONS. THIS RESEARCH WILL HELP US TO DEVELOP BETTER VACCINES AND THERAPEUTIC AGENTS FOR VIRAL INFECTIONS. THIS PROGRAM INCLUDES PRE-CLINICAL WORK ON A NOVEL UNIVERSAL INFLUENZA VACCINE, THE MECHANISM BY WHICH IT PROTECTS AGAINST MULTIPLE STRAINS OF INFLUENZA AND WHETHER THE VACCINE PROTECTS AGAINST SECONDARY BACTERIAL INFECTIONS OFTEN INCREASE MORTALITY FROM INFLUENZA. WE ARE ALSO INVESTIGATING NOVEL VACCINE ADJUVANTS AND WHY IMMUNE RESPONSES TO CERTAIN VACCINES WANE OVER TIME.

Program 2
Expenses: $171,971 Revenue: $178,181

DIABETESTHE GOAL OF THIS PROGRAM IS TO IDENTIFY UNIQUE EVENTS AND MOLECULAR PATHWAYS THAT CAN TRIGGER THE AUTOREACTIVE T CELLS TO CAUSE DESTRUCTION OF THE PANCREATIC ISLETS IN TYPE 1 DIABETES. THE...

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DIABETESTHE GOAL OF THIS PROGRAM IS TO IDENTIFY UNIQUE EVENTS AND MOLECULAR PATHWAYS THAT CAN TRIGGER THE AUTOREACTIVE T CELLS TO CAUSE DESTRUCTION OF THE PANCREATIC ISLETS IN TYPE 1 DIABETES. THE ROLE OF EXOSOMES AND NOVEL SELF-ANTIGENS ENCODED BY ENDOGENOUS RETROVIRUSES IS A MAJOR FOCUS OF THIS STUDY.

Program 3

THE BLOOD BRAIN BARRIERTHE BLOOD-BRAIN BARRIER (BBB) PREVENTS BLOODBORNE SUBSTANCES FROM NON-SELECTIVELY CROSSING INTO THE BRAIN AND PLAYS A CRUCIAL ROLE IN PROTECTING THE BRAIN FROM HARMFUL...

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THE BLOOD BRAIN BARRIERTHE BLOOD-BRAIN BARRIER (BBB) PREVENTS BLOODBORNE SUBSTANCES FROM NON-SELECTIVELY CROSSING INTO THE BRAIN AND PLAYS A CRUCIAL ROLE IN PROTECTING THE BRAIN FROM HARMFUL SUBSTANCES AND PATHOGENS. HOWEVER, THE BBB ALSO SIGNIFICANTLY IMPEDES THE DELIVERY OF THERAPEUTIC AGENTS INTO THE BRAIN WHICH PRESENTS A MAJOR CHALLENGE FOR THE TARGETING AND DELIVERY OF PHARMACOLOGICAL AGENTS FOR THE TREATMENT OF VARIOUS CENTRAL NERVOUS SYSTEM (CNS) DISEASES, INCLUDING CANCERS, HIV INFECTION AND ALZHEIMER'S DISEASE. BRISC SCIENTISTS ARE STUDYING THE ROLE OF THE BBB IN HEALTH AND DISEASE AND ARE CONDUCTING COLLABORATIVE STUDIES ON NOVEL METHODS OF REVERSIBLY PERMEABILIZING THE BBB TO ALLOW ENTRY OF THERAPEUTIC AGENTS.

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Trantor Score

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Liquidity (40%) • Solvency (30%) • Sustainability (20%) • Efficiency (10%)

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Financial Overview (2023)

Revenue Breakdown

Contributions & Grants $178,181
Program Service Revenue $0
Investment Income $0
Other Revenue $30,068
TOTAL REVENUE $208,249

Expense Breakdown

Grants Paid $0
Salaries & Benefits $101,118
Fundraising Expenses $0
Program Expenses $171,971
Other Expenses $87,877
TOTAL EXPENSES $188,995

Year-over-Year Comparison

2023 2022 Change
Revenue $208,249 $72,428 +1.9%
Expenses $188,995 $91,029 +1.1%
Net Income $19,254 $-18,601 -2.0%
Key Indicators
Grants to Organizations Grants to Individuals Lobbying Political Activity Foreign Activities Donor Advised Fund Schedule B Required
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Liquidity & Cash Position

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Governance

Voting Members
4
Independent Members
3
Employees
3
Volunteers
N/A

Governance Policies

Conflict of Interest Policy
Whistleblower Policy
Document Retention Policy

Special Practices & Reported Activities

Operated a School
Operated a Hospital
Provided First Class Travel
Reported Conflict of Interest
Reported Asset Diversion
Excess Benefit Transaction
Made Political Expenditures
Engaged in Lobbying
Operated Donor Advised Fund
Maintained Art Collections
Filed Form 720

Compensation of Officers, Directors & Key Employees

Total Officers
2
$34,683
Total Directors
4
$0
Key Employees
0
$0
Highest Compensated
0
reported
Name Title Hours/Week Role Reportable Comp Other Comp Total
DR CRAIG JACKSON CHAIRMAN OF BOARD OF DIREC 0.50
Director
$0 $0 $0
DR LEMAN YEL DIRECTOR 0.30
Director
$0 $0 $0
DR PETER DIAS CFO 20.00
Officer Director
$0 $0 $0
MR MICHAEL GISKE DIRECTOR 0.50
Director
$0 $0 $0
DR SALLY SARAWAR PRESIDENT AND CEO 20.00
Officer
$34,683 $0 $34,683
Note: Compensation data is self-reported by the organization on their Form 990. "Reportable Comp" includes salary, bonuses, and other reportable compensation from the organization and related organizations. "Other Comp" includes benefits, deferred compensation, and non-taxable benefits.

Historical Data

Year Revenue Expenses Assets Net Income
2023 $208,249 $188,995 $60,330 $19,254
2020 $352,753 $352,568 $52,606 $185
2019 $924,036 $923,840 $52,547 $196
2018 $818,213 $818,116 $83,144 $97
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