HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE

RESEARCH ADMINISTRATION EXPENSES: AS A TRUSTED PARTNER WITH MILITARY MEDICAL RESEARCHERS, IMPORTANT HJF ACCOMPLISHMENTS INCLUDE ATTRACTING, MANAGING, AND RETAINING HIGHLY QUALIFIED SCIENTIFIC STAFF TO SUPPORT THE PRIORITIES OF U.S. MILITARY MEDICINE. WHETHER IT IS THE SENIOR SCIENTIST TO LEAD MAJOR INITIATIVES AND WORK COLLABORATIVELY WITH U.S. GOVERNMENT SCIENTISTS, OR LAB TECHS TO PERFORM ONGOING RESEARCH FUNCTIONS, HJF HIRES THE BEST AND BRIGHTEST TALENT TO ACCELERATE INNOVATIONS NECESSARY TO ADVANCE MILITARY MEDICINE. IN FY2025, HJF PLAYED AN EVEN LARGER ROLE IN CONVENING AND CONNECTING THE MILITARY, INDUSTRY, ACADEMIA, AND GOVERNMENT BY HOSTING LEADERSHIP FORA AND OTHER KEY DOD MEDICINE MEETINGS, WITH GOVERNMENTAL AND NON-GOVERNMENTAL THOUGHT LEADERS, TO COLLABORATIVELY IDENTIFY CHALLENGES AND POSIT MILITARY MEDICINE SOLUTIONS. ADDITIONALLY, IN FY2025 HJF BEGAN CONSTRUCTION OF HJF INNOVATION LABS @ MONTGOMERYCOUNTYMD (HIL), AS PART OF THE HJF INNOVATION ECOSYSTEM INITIATIVE. DESIGNED TO SERVE AS A UNIQUE REGIONAL BIOTECH INCUBATOR, THIS NEW FACILITY IS DESIGNED TO SPECIFICALLY ADDRESS THE CHALLENGES FACED BY GROWING STARTUPS AND SMALL COMPANIES. THE PRIMARY FOCUS OF THE HIL IS TO ACCELERATE THE AVAILABILITY OF RELEVANT MEDICAL PRODUCTS AND SERVICES TO OUR NATION'S WARFIGHTERS, VETERANS, AND CIVILIANS. HJF AIMS TO ASSIST BIOTECH AND MEDICAL DEVICE STARTUPS SURMOUNT FINANCIAL CONSTRAINTS AND NAVIGATE THE INS AND OUTS OF DUAL USE MILITARY MEDICAL TECHNOLOGY DEVELOPMENT. HJF SUPPORTED PROGRAMS: UNIFORMED SERVICES UNIVERSITY (USU) BRAIN TISSUE REPOSITORY: HJF WAS SELECTED TO RECEIVE A CHARITABLE GIFT FROM RETIRED ADMIRAL WILLIAM MCRAVEN, AS PART OF A $50 MILLION 2024 BEZOS COURAGE AND CIVILITY AWARD. FOR THIS AWARD, RETIRED ADMIRAL MCRAVEN CHOSE TO SUPPORT ONE OF THE WORLD'S LEADING EXPERTS ON TRAUMATIC BRAIN INJURY (TBI) IN MILITARY PERSONNEL: DANIEL PERL, M.D., FRSM. DR. PERL IS THE DIRECTOR OF THE DEPARTMENT OF WAR/UNIFORMED SERVICES UNIVERSITY BRAIN TISSUE REPOSITORY AND PROFESSOR OF PATHOLOGY (NEUROPATHOLOGY) AT USU WHERE HE HAS BEEN CONDUCTING TBI RESEARCH FOR 15 YEARS. THIS NEW PROJECT, TITLED, "UNVEILING CELLULAR MECHANISMS OF BLAST-INDUCED TBI THROUGH ADVANCED SPATIAL GENOMICS," WILL INVESTIGATE "INTERFACE ASTROGLIAL SCARRING," A SPECIFIC PATTERN OF BRAIN DAMAGE HE FIRST IDENTIFIED IN BLAST-EXPOSED SERVICE MEMBERS. THE U.S. MILITARY HIV RESEARCH PROGRAM (MHRP): MHRP, THE WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR), HJF, AND PARTNERS COMPLETED ENROLLMENT IN A PHASE 1 HUMAN TRIAL IN TANZANIA TO EVALUATE THE SAFETY AND ANTIVIRAL ACTIVITY OF A LONG-ACTING BISPECIFIC ANTIBODY, ALONE AND IN COMBINATION WITH ANOTHER POTENT MONOCLONAL ANTIBODY (MAB), TO COMBAT HIV. THE TRIAL IS ALSO EXPLORING FIXED DOSING AND THE SAFETY OF INTRAMUSCULAR INJECTION TO DELIVER THESE MABS, IMPORTANT ADVANTAGES FOR FUTURE POTENTIAL USE IN REMOTE OR MILITARY SETTINGS WHERE MEDICAL INFRASTRUCTURE MAY BE LIMITED. THESE MABS MAY BE USED IN GEOGRAPHIES STRATEGIC TO THE U.S. MILITARY WHERE HIV IS HIGHLY ENDEMIC, INCLUDING EXPANSION TO THE INDO-PACIFIC COMMAND REGION. MHRP'S LONG-TIME COLLABORATOR, TANZANIA'S NATIONAL INSTITUTE FOR MEDICAL RESEARCH - MBEYA MEDICAL RESEARCH CENTER, IS CONDUCTING THE STUDY, CALLED RV584. WALTER REED NATIONAL MILITARY MEDICAL CENTER (WRNMMC): HJF RECEIVED FUNDING THROUGH A GRANT FROM WOUNDED WARRIOR PROJECT(R) (WWP) TO SUPPORT THE WORK OF THE 7 EAST BRAIN INJURY MEDICINE/NEUROPSYCHIATRY PROGRAM AT WRNMMC. THE PROGRAM TREATS BRAIN INJURIES OF ALL SEVERITIES, FROM MILD CONCUSSIVE INJURIES TO SEVERE INJURIES REQUIRING SURGERY, COMBINING MEDICAL, SURGICAL, AND BEHAVIORAL HEALTH CARE TO ADDRESS THE FULL SPECTRUM OF COMPLICATIONS FROM TRAUMATIC BRAIN INJURY. IN FY2025, HJF MANAGED MORE THAN 800 AWARDS, GRANTS, AGREEMENTS, OR CONTRACTS, MORE THAN 1,500 ACTIVE CLINICAL STUDIES (HUMAN AND ANIMAL PROTOCOLS), AND MORE THAN 50 ACTIVE LICENSE AGREEMENTS. HJF HAS MORE THAN 2,900 TEAMMATES AT SITES ON FOUR CONTINENTS.

ENDOWMENTS: ENDOWMENTS DELIVERED SIGNIFICANT PROGRAM SERVICES AND SUPPORT TO THE UNIFORM SERVICES UNIVERSITY FOR THE HEALTH SCIENCES (USU) PARTICULARLY FOR THE SCHOOL OF MEDICINE AND THE CLINICAL SCIENCES DEPARTMENT OF SURGERY AND DEPARTMENT OF DERMATOLOGY. PROGRAMS INCLUDE FELLOWSHIP GRANTS FOR GRADUATE STUDENTS STUDYING MEDICINE AT USU. HJF FELLOWSHIP AWARDS PROVIDE TRAVEL, EDUCATIONAL, AND TRAINING SUPPORT.