Howard Hughes Medical Institute

EIN: 590735717 501(c)(3) Medical Research

CHEVY CHASE, MD

Total Revenue
$2,004,784,057
Total Expenses
$1,178,202,544
Total Assets
$29,497,763,012
Net Assets
$27,618,269,570
🔒

Financial Vulnerability Assessment (Tuckman-Chang)

4 risk indicators measuring financial stability and operational resilience

Sign in with your work email to view Tuckman-Chang indicators

Sign In — Free (10 views/day)

Financial Trends

Organization Details

Formation Year
1953
Legal Domicile
DE
Phone
3012158500
Tax Period
2024-09-01 to 2025-08-31

Howard Hughes Medical Institute, founded in 1953, is a large national nonprofit in the Medical Research sector that reported $2.0B in total revenue in fiscal year 2024. Revenue grew 14% year-over-year, indicating healthy expansion. The organization ran a surplus of $826.6M, a strong 41% operating margin.

Mission

THE HOWARD HUGHES MEDICAL INSTITUTE IS A BIOMEDICAL RESEARCH ORGANIZATION DEDICATED TO CONDUCTING FUNDAMENTAL RESEARCH IN THE LIFE SCIENCES, SUPPORTING SCIENCE EDUCATION THROUGHOUT THE UNITED STATES, AND ADVANCING THE PUBLIC UNDERSTANDING OF SCIENCE.

🔒

Trantor Score

Financial Health Score (300–850) · Liquidity · Solvency · Sustainability · Efficiency

Sign in to view Trantor Score and financial metrics

Liquidity (40%) • Solvency (30%) • Sustainability (20%) • Efficiency (10%)

Sign In — Free (10 views/day)

Financial Overview (2024)

Revenue Breakdown

Contributions & Grants $1,783,098
Program Service Revenue $4,608,732
Investment Income $1,966,414,132
Other Revenue $31,978,095
TOTAL REVENUE $2,004,784,057

Expense Breakdown

Grants Paid $63,319,232
Salaries & Benefits $490,580,362
Fundraising Expenses $0
Program Expenses $944,508,067
Other Expenses $624,302,950
TOTAL EXPENSES $1,178,202,544

Year-over-Year Comparison

2024 2023 Change
Revenue $2,004,784,057 $1,760,221,928 +0.1%
Expenses $1,178,202,544 $1,152,447,870 +0.0%
Net Income $826,581,513 $607,774,058 +0.4%
Key Indicators
Grants to Organizations Grants to Individuals Lobbying Political Activity Foreign Activities Donor Advised Fund Schedule B Required
🔒

Financial Health Indicators

Comprehensive financial analysis: Altman Z-Score, liquidity, solvency, sustainability, efficiency, and growth metrics

Financial Distress Indicator

Liquidity & Cash Position

Sign in to view all financial metrics

Altman Z-Score • Liquidity Ratios • Solvency Analysis • Growth Indicators • Efficiency Metrics

Sign In

Governance

Voting Members
12
Independent Members
12
Employees
2627
Volunteers
N/A

Governance Policies

Conflict of Interest Policy
Whistleblower Policy
Document Retention Policy

Special Practices & Reported Activities

Operated a School
Operated a Hospital
Provided First Class Travel
Reported Conflict of Interest
Reported Asset Diversion
Excess Benefit Transaction
Made Political Expenditures
Engaged in Lobbying
Operated Donor Advised Fund
Maintained Art Collections
Filed Form 720

Compensation of Officers, Directors & Key Employees

Total Officers
12
$9,681,295
Total Directors
13
$785,000
Key Employees
0
$0
Highest Compensated
5
reported
Name Title Hours/Week Role Reportable Comp Other Comp Total
ALISON F RICHARD PHD TRUSTEE 3.0
Director
$70,000 $0 $70,000
CHARLENE BARSHEFSKY ESQ TRUSTEE, CHAIR NOM & GOV COMM 4.0
Director
$87,500 $0 $87,500
CLAYTON S ROSE PHD TRUSTEE, CHAIR 6.0
Director
$100,000 $0 $100,000
DAVID JULIUS PHD TRUSTEE, CHAIR RESEARCH COMM 3.0
Director
$60,000 $0 $60,000
DEBORA L SPAR PHD TRUSTEE, CHAIR AUDIT & COMP 4.0
Director
$70,000 $0 $70,000
EDITH HEARD PHD TRUSTEE (AS OF 02/25)/ADVISORY BOARD MEMBER (2024) 2.0
Director
$12,500 $0 $12,500
FRED R LUMMIS TRUSTEE, CHAIR FINANCE COMM 4.0
Director
$70,000 $0 $70,000
JAY JACOBS TRUSTEE (AS OF 11/24) 2.0
Director
$15,000 $0 $15,000
JOSEPH L GOLDSTEIN MD TRUSTEE 3.0
Director
$70,000 $0 $70,000
KURT L SCHMOKE ESQ TRUSTEE (THRU 10/24) 2.0
Director
$50,000 $0 $50,000
MARGARET D TUTWILER TRUSTEE 2.0
Director
$60,000 $0 $60,000
PAUL M NURSE PHD TRUSTEE 2.0
Director
$60,000 $0 $60,000
RISA LAVIZZO-MOUREY MD MBA TRUSTEE, CHAIR EDUCATION COMM 3.0
Director
$60,000 $0 $60,000
BLANTON TOLBERT PHD VP SCIENCE LEADERSHIP AND CULTURE (THRU 05/25)/LAB HEAD 40.0
Officer
$778,489 $54,879 $833,368
BODO STERN PHD CHIEF OF STRATEGIC INITIATIVES 40.0
Officer
$446,695 $54,115 $500,810
DONALD KOCH VP & CHIEF INVESTMENT OFFICER 40.0
Officer
$1,928,020 $76,946 $2,004,966
ERIN K O'SHEA PHD PRESIDENT 40.0
Officer
$1,652,120 $69,264 $1,721,384
HEIDI E HENNING ESQ VP & GENERAL COUNSEL & SECRETARY 40.0
Officer
$831,890 $55,620 $887,510
JEREMY COMPTON CONTROLLER 40.0
Officer
$265,218 $40,264 $305,482
KRISTIAN GREENE DIRECTOR, TREASURY OPERATIONS & ASSISTANT TREASURER 40.0
Officer
$176,055 $55,676 $231,731
KRISTINA HEIBERGER ESQ DEPUTY GENERAL COUNSEL & ASSISTANT SECRETARY 40.0
Officer
$425,011 $82,272 $507,283
LESLIE B VOSSHALL PHD VP & CHIEF SCIENTIFIC OFFICER 40.0
Officer
$772,292 $78,035 $850,327
LYNNE LOCHTE CHIEF FINANCIAL OFFICER & TREASURER 40.0
Officer
$481,161 $53,729 $534,890
NELSON SPRUSTON PHD VP & EXEC DIR, JANELIA RESEARCH CAMPUS 40.0
Officer
$643,812 $71,571 $715,383
SETH GROSSMAN ESQ VP, CHIEF OPERATING OFFICER & SENIOR ADVISOR TO THE PRESIDENT 40.0
Officer
$541,218 $46,943 $588,161
GLEN ZWICKER MANAGING DIRECTOR & HEAD OF INVESTMENT OPERATIONS 40.0
Highest
$1,043,689 $74,835 $1,118,524
KAREN EIFLER MANAGING DIRECTOR, PUBLIC MARKETS 40.0
Highest
$1,160,055 $36,152 $1,196,207
MARK SPROLES MANAGING DIRECTOR, PRIVATE MARKETS 40.0
Highest
$1,207,419 $36,651 $1,244,070
RICHARD AXEL MD INVESTIGATOR 40.0
Highest
$806,661 $48,264 $854,925
RONALD VALE PHD SENIOR GROUP LEADER/FORMER VP & EXEC. DIR., JRC 40.0
Highest
$769,522 $56,548 $826,070
DAVID E CLAPHAM PHD SENIOR GROUP LEADER/FORMER VP & CHIEF SCIENTIFIC OFFICER 40.0
$590,291 $73,447 $663,738
GERALD M RUBIN PHD SENIOR GROUP LEADER/FORMER VP & EXEC. DIR., JRC 40.0
$599,415 $62,422 $661,837
NATASHA NEISES SENIOR DIRECTOR, FINANCIAL PLANNING & ANALYSIS 40.0
$294,592 $45,058 $339,650
SEAN B CARROLL PHD INVESTIGATOR/FORMER VP SCI. & ED. MEDIA GROUP 40.0
$593,698 $61,567 $655,265
Note: Compensation data is self-reported by the organization on their Form 990. "Reportable Comp" includes salary, bonuses, and other reportable compensation from the organization and related organizations. "Other Comp" includes benefits, deferred compensation, and non-taxable benefits.

Historical Data

Year Revenue Expenses Assets Net Income
2025 $2,004,784,057 $1,178,202,544 $29,497,763,012 $826,581,513
2024 $1,760,221,928 $1,152,447,870 $27,296,895,597 $607,774,058
2023 $749,022,788 $1,147,090,579 $25,892,499,538 $-398,067,791
2022 $2,117,477,557 $986,289,955 $25,877,392,654 $1,131,187,602
2021 $2,096,794,078 $954,764,083 $29,343,107,763 $1,142,029,995
2020 $1,467,289,681 $947,377,660 $23,840,455,852 $519,912,021
2019 $1,411,381,183 $1,081,673,510 $22,544,411,510 $329,707,673
2018 $1,527,324,317 $925,718,713 $23,816,259,445 $601,605,604
Explore More Nonprofits
Top 100 Nonprofits in Maryland Largest U.S. Nonprofits Best Rated Nonprofits Most Efficient Nonprofits

Compare Howard Hughes Medical Institute with other nonprofits in Maryland and across the country.