Human Proteome Organization - HUPO (EIN 800814948) - Form 990 Financial Analysis & Trantor Score

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Financial Vulnerability Assessment (Tuckman-Chang)

4 risk indicators measuring financial stability and operational resilience

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Financial Trends

Organization Details

Formation Year

2004

Legal Domicile

Phone

6045585498

Tax Period

2024-01-01 to 2024-12-31

Human Proteome Organization - HUPO, founded in 2004, is a small nonprofit in the Medical Research sector that reported $233K in total revenue in fiscal year 2024. Revenue fell 85% from the prior year — a significant decline worth monitoring. Expenses of $299K exceeded revenue, resulting in a 28% operating deficit.

Mission

promote the development and application of proteome technologies to enhance biological knowledge, global health and wellness through international collaboration, coordination, education and advocacy in an inclusive and empowering environment.

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Trantor Score

Financial Health Score (300–850) · Liquidity · Solvency · Sustainability · Efficiency

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Liquidity (40%) • Solvency (30%) • Sustainability (20%) • Efficiency (10%)

Financial Overview (2024)

Revenue Breakdown

Contributions & Grants $0

Program Service Revenue $223,365

Investment Income $9,060

Other Revenue $600

TOTAL REVENUE $233,025

Expense Breakdown

Grants Paid $0

Salaries & Benefits $0

Fundraising Expenses $0

Program Expenses $230,385

Other Expenses $298,545

TOTAL EXPENSES $298,545

Year-over-Year Comparison

	2024	2023	Change
Revenue	$233,025	$1,547,525	-0.8%
Expenses	$298,545	$1,340,145	-0.8%
Net Income	$-65,520	$207,380	-1.3%

Key Indicators

✗ Grants to Organizations ✗ Grants to Individuals ✗ Lobbying ✗ Political Activity ✗ Foreign Activities ✗ Donor Advised Fund ✗ Schedule B Required

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Financial Health Indicators

Comprehensive financial analysis: Altman Z-Score, liquidity, solvency, sustainability, efficiency, and growth metrics

Financial Distress Indicator

Liquidity & Cash Position

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Altman Z-Score • Liquidity Ratios • Solvency Analysis • Growth Indicators • Efficiency Metrics

Governance

Voting Members

Independent Members

Employees

N/A

Volunteers

N/A

Governance Policies

✗ Conflict of Interest Policy

✗ Whistleblower Policy

✗ Document Retention Policy

Special Practices & Reported Activities

✗ Operated a School

✗ Operated a Hospital

✗ Provided First Class Travel

✗ Reported Conflict of Interest

✗ Reported Asset Diversion

✗ Excess Benefit Transaction

✗ Made Political Expenditures

✗ Engaged in Lobbying

✗ Operated Donor Advised Fund

✗ Maintained Art Collections

✗ Filed Form 720

Compensation of Officers, Directors & Key Employees

Total Officers

Total Directors

Key Employees

Highest Compensated

reported

Name	Title	Hours/Week	Role	Reportable Comp	Other Comp	Total
see attached list of	Officers	0.50	Officer	$0	$0	$0
executive committee members	Officers	0.50	Officer	$0	$0	$0

Note: Compensation data is self-reported by the organization on their Form 990. "Reportable Comp" includes salary, bonuses, and other reportable compensation from the organization and related organizations. "Other Comp" includes benefits, deferred compensation, and non-taxable benefits.

Historical Data

Year	Revenue	Expenses	Assets	Net Income
2024	$233,025	$298,545	$1,062,343	$-65,520
2023	$1,547,525	$1,340,145	$1,059,231	$207,380
2022	$1,065,685	$899,807	$1,100,150	$165,878
2021	$537,131	$490,556	$683,130	$46,575
2020	$340,198	$242,218	$624,533	$97,980
2019	$169,013	$167,396	$529,195	$1,617

Human Proteome Organization - HUPO