POLYBIO RESEARCH FOUNDATION INC

EIN: 845157239 501(c)(3)

MEDFORD, MA

Total Revenue
$4,324,689
Total Expenses
$14,142,012
Total Assets
$9,811,535
Net Assets
$3,095,960
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Financial Vulnerability Assessment (Tuckman-Chang)

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Financial Trends

Organization Details

Formation Year
2020
Legal Domicile
WA
Principal Officer
AMY PROAL
Phone
9178480238
Tax Period
2024-01-01 to 2024-12-31

POLYBIO RESEARCH FOUNDATION INC, founded in 2020, is a community nonprofit that reported $4.3M in total revenue in fiscal year 2024. Revenue fell 75% from the prior year — a significant decline worth monitoring. Expenses of $14.1M exceeded revenue, resulting in a 227% operating deficit.

Mission

WE ARE A 501(C)3 TRANSFORMING HOW COMPLEX CHRONIC CONDITIONS LIKE LONGCOVID, ME/CFS & POST TREATMENT LYME DISEASE ARE STUDIED, DIAGNOSED, AND TREATED. POLYBIO WAS FOUNDED BY THREE SCIENTISTS WITH COMPLEMENTARY EXPERTISE (NEUROSCIENCE, MICROBIOLOGY & GENETICS). WE CONCEPTUALIZE RESEARCH PROJECTS THAT IDENTIFY ROOT CAUSE DRIVERS OF THESE CONDITIONS AND BUILD COLLABORATIVE TEAMS TO MAKE THE PROJECTS A REALITY.

Program Service Accomplishments

Program 1
Expenses: $14,046,841

WE CONCEPTUALIZE COLLABORATIVE RESEARCH PROJECTS ON ME/CFS, LONGCOVID AND RELATED INFECTION-ASSOCIATED CHRONIC CONDITIONS. OUR PROJECTS STUDY "ROOT CAUSE" DRIVERS OF THESE CONDITIONS, AND COMBINE THE...

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WE CONCEPTUALIZE COLLABORATIVE RESEARCH PROJECTS ON ME/CFS, LONGCOVID AND RELATED INFECTION-ASSOCIATED CHRONIC CONDITIONS. OUR PROJECTS STUDY "ROOT CAUSE" DRIVERS OF THESE CONDITIONS, AND COMBINE THE SKILLS OF VIROLOGISTS, NEUROSCIENTISTS, PATHOLOGISTS, MICROBIOME EXPERTS AND PATIENT ADVOCATES TO MAXIMIZE IMPACT.

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Trantor Score

Financial Health Score (300–850) · Liquidity · Solvency · Sustainability · Efficiency

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Liquidity (40%) • Solvency (30%) • Sustainability (20%) • Efficiency (10%)

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Financial Overview (2024)

Revenue Breakdown

Contributions & Grants $4,095,453
Program Service Revenue $0
Investment Income $229,236
Other Revenue $0
TOTAL REVENUE $4,324,689

Expense Breakdown

Grants Paid $13,813,525
Salaries & Benefits $193,605
Fundraising Expenses $27,634
Program Expenses $14,046,841
Other Expenses $134,882
TOTAL EXPENSES $14,142,012

Year-over-Year Comparison

2024 2023 Change
Revenue $4,324,689 $17,350,488 -0.8%
Expenses $14,142,012 $18,634,620 -0.2%
Net Income $-9,817,323 $-1,284,132 +6.6%
Key Indicators
✓ Grants to Organizations ✓ Grants to Individuals ✗ Lobbying ✗ Political Activity ✗ Foreign Activities ✗ Donor Advised Fund ✓ Schedule B Required
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Financial Health Indicators

Comprehensive financial analysis: Altman Z-Score, liquidity, solvency, sustainability, efficiency, and growth metrics

Financial Distress Indicator

Liquidity & Cash Position

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Altman Z-Score • Liquidity Ratios • Solvency Analysis • Growth Indicators • Efficiency Metrics

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Governance

Voting Members
6
Independent Members
6
Employees
1
Volunteers
5

Governance Policies

✓ Conflict of Interest Policy
✓ Whistleblower Policy
✓ Document Retention Policy

Special Practices & Reported Activities

✗ Operated a School
✗ Operated a Hospital
✗ Provided First Class Travel
✗ Reported Conflict of Interest
✗ Reported Asset Diversion
✗ Excess Benefit Transaction
✗ Made Political Expenditures
✗ Engaged in Lobbying
✗ Operated Donor Advised Fund
✗ Maintained Art Collections
✗ Filed Form 720

Compensation of Officers, Directors & Key Employees

Total Officers
7
$185,000
Total Directors
7
$185,000
Key Employees
0
$0
Highest Compensated
0
reported
Name Title Hours/Week Role Reportable Comp Other Comp Total
AMY PROAL EXECUTIVE DIRECTOR 40.00
Officer Director
$185,000 $0 $185,000
MICHAEL VANELZAKKER DIRECTOR 3.00
Officer Director
$0 $0 $0
CHARLOTTE MAO CLERK 3.00
Officer Director
$0 $0 $0
MARK LONGSTRETH TREASURER 2.00
Officer Director
$0 $0 $0
MAGGIE STEFFENS DIRECTOR 1.00
Officer Director
$0 $0 $0
KATHRYN BACH DIRECTOR 3.00
Officer Director
$0 $0 $0
FRANCIS BRENNER CHAIR 3.00
Officer Director
$0 $0 $0
Note: Compensation data is self-reported by the organization on their Form 990. "Reportable Comp" includes salary, bonuses, and other reportable compensation from the organization and related organizations. "Other Comp" includes benefits, deferred compensation, and non-taxable benefits.

Historical Data

Year Revenue Expenses Assets Net Income
2024 $4,324,689 $14,142,012 $9,811,535 $-9,817,323
2023 $17,350,488 $18,634,620 $15,536,208 $-1,284,132
2022 $17,879,554 $4,294,270 $14,198,872 $13,585,284
2021 $622,734 $34,354 $614,801 $588,380
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